Apply only to affected areas of the skin

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Pharmachologic effect

Acticin Permethrin

Permetric ointment / gel / cream is an insecticidal and acaricidal preparation for topical application. The active component is permethrin, a mixture of trans- and cis-isomers of a synthetic pyrethroid. Permethrin is active against a number of insects, including scabies mite. Permethrin causes death and developmental disorders, both of larvae and sexually mature individuals. The mechanism of action of the drug is based on the ability of permethrin to disrupt the ion current through the sodium channels, which leads to disruption of the polarization of the membrane of nerve cells of insects and paralysis of the insect. Permetrin has practically no toxic effect on human cells and warm-blooded animals.

Systemic absorption of permethrin with external application is no more than 2%. Permethrin, which enters the systemic circulation, is metabolized with the formation of pharmacologically inactive metabolites. Metabolites of permethrin are excreted mainly by the kidneys.

Indications for use

Permetric ointment is intended for local therapy of patients suffering from acne, scabies, including complicated secondary flora.

Permetric ointment can be effective for parasites (including lice).

Mode of application

Permetric ointment is intended for external use. The drug Permetrine ointment is recommended to apply a thin layer, gently rubbing. It is desirable to apply the ointment only to the areas of the skin, affected by scabies. After 24 hours after applying Permetrine ointment, you should wash the skin with soap and change your clothes. It is advisable to avoid getting the drug permetrine ointment into the eyes (if the drug has got into the eye, it should be washed with plenty of clean running water). Avoid contact with permetrine ointment on mucous membranes (including mucous membranes of the nose, mouth and genital organs). After applying the ointment, you should thoroughly wash your hands. The use of ointment is allowed only in well-ventilated rooms or on the street.

Permethrin-cream on skin

The drug is usually prescribed once. In case of the appearance of new foci of scabies, you should reapply the ointment 2 weeks after the first application of Permetrine ointment.

It is recommended to wash off the permethrin ointment 12 hours after application.

In case of severe itching, repeated application of the ointment is allowed 1-2 days after the first use of the drug Permetrine ointment.

The maximum recommended duration of treatment includes 5 applications of the drug Permetrine ointment.

In the event that the full course of treatment with the drug Permetrine Ointment did not give the expected therapeutic effect, a second examination should be carried out.

After each use of the drug, bed linen and clothing should be cleaned using high temperatures (steam or hot water).

Side effects

Permetrine ointment, as a rule, is well tolerated by patients. Individual cases of local allergic reactions, as well as burning, numbness and itching at the application site have been reported. In single cases, when using the drug Permetrine ointment in patients, the development of erythema is possible.

With the development of unwanted effects of permetrine ointment drug should be discarded.


Permetrin ointment is not prescribed to patients with individual hypersensitivity to the ingredients of the drug.

Permethrin ointment is not used for the treatment of children under 3 years of age, pregnant and lactating women.


Permetrine ointment is not recommended for pregnant and lactating women. If you avoid the appointment of the drug Permetrine Ointment during lactation, you should not decide whether to interrupt breastfeeding.

Drug Interactions

Do not apply Permetrine ointment on one skin area with other topical medications.


With external application of the drug Permetrine ointment, the development of overdose is impossible.
If you accidentally swallow the ointment, you should immediately wash the stomach and take enterosorbent funds. In case of development of undesirable effects it is necessary to address to the doctor who will appoint or nominate symptomatic agents.

Form of issue

Ointment in tubes of aluminum for 30, 50 or 90 g in tubes, in a cardboard bundle 1 bundle is enclosed.

Storage conditions

Preparation Permetrine ointment should be stored no more than 2 years after manufacturing in rooms with room temperature.

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Apply only to affected areas of the skin Update December 20, 2019 Autor: solien